Endocrine Abstracts

Noninfectious pneumonitis is a recognised toxicity associated with mTOR inhibitors, such as everolimus. We report a 75 year old female with histologically confirmed on colonoscopy, non-functioning Grade 2 (Ki 9%) in situ terminal ileal NET with ileocolic lymphadenopathy and multiple liver metastases, who was commencedon somatostatin analogue therapy at presentation in May 2017, but developed progressive disease on CT by February 2018. Based on RADIANT – 4 which s...

A 51 year old female patient presented in 2000 with a 7 month history of diarrhoea and weight loss. Bloods revealed hypokalaemia (1.9). Infection and malabsorption screen negative, but patient remained hypokalaemic despite maximum iv and oral replacement. No abnormality was found endoscopically. Fasting gut hormone profile showed raised Vasoactive Intestinal Polypeptide (VIP) >400 (NR <30). CT scan confirmed 5cm mass in body of pancreas, no metastatic disease. Response...